Effects of FKBP5 on Stroke Outcome in Mice and Men—a Translational Study

20260 citationsJournal Article

Authors

Thomas G. Liman · Carl von Ossietzky Universität Oldenburg

Marie‐Louise Herzog · Humboldt-Universität zu Berlin

Darina Czamara · Max Planck Institute of Psychiatry

Ria Göttert · Humboldt-Universität zu Berlin

Markus A. Schmidt · Max Planck Institute of Psychiatry

Golo Kronenberg · Klinik für Psychosomatik

Elisabeth B. Binder

Abstract

Loss of Fkbp5 leads to improved outcome in experimental stroke. In addition, the FKBP5 risk haplotype, indicative of increased FKBP5 expression, was associated with poor functional outcome following stroke.

Topics & Keywords

Signaling Pathways in Disease Aldose Reductase and Taurine Heat shock proteins research

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Stroke

DOI: 10.1161/strokeaha.125.052905

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