Health-related quality of life after definitive chemoradiotherapy in patients with esophageal carcinoma: a population-based analysis

Our study showed that where global health status remained stable from 6 months after dCRT, the burden of disease-specific symptoms decreased. Social and cognitive functioning first deteriorated but recovered over time, whereas the decline in physical functioning, role functioning, fatigue and dyspnea did not recover to baseline level. These findings can provide valuable insights to address concerns regarding the impact of dCRT on HRQoL within the context of shared decision-making.