Dietary Choline and Betaine Intake and 2-year Changes in Cognitive Function in Older Adults With Overweight or Obesity and Metabolic Syndrome: A Prospective Cohort Analysis

20260 citationsJournal Articlehybrid Open Access

Authors

Héctor Vázquez-Lorente · Institut de Recerca Biomèdica Catalunya Sud

José María Manzanares

Nancy Babio · Institut de Recerca Biomèdica Catalunya Sud

Miguel Ruiz-Canela · Instituto de Salud Carlos III

Dolores Corella · Universitat de València

Javi Hernando · Instituto de Salud Carlos III

J. Alfredo Martínez · Instituto de Salud Carlos III

Abstract

Higher dietary choline and betaine intake were associated with modest short-term improvements in cognitive performance over 2 y in older adults. Longer-term studies are warranted. This trial was registered at www.isrctn.com as ISRCTN89898870.

Topics & Keywords

Folate and B Vitamins Research Alcoholism and Thiamine Deficiency Nutritional Studies and Diet

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: American Journal of Clinical Nutrition

Volume 123, Issue 5, pp. 101265-101265

DOI: 10.1016/j.ajcnut.2026.101265

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