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Objective: It is 2024, and the debate of physician-assisted suicide and euthanasia remains highly complex and impactful. This discussion extends to the legal and ethical theories that affect these issues, but also profoundly impact real lives and families. Understanding where we stand today requires a look back at historical contexts and current perspectives, while pointing out the necessity of raising awareness concerning educating healthcare professionals and the role of palliative care. Methods: A review of historical developments, legal cases, and current perspectives related to physician assisted suicide and euthanasia was conducted to understand how these practices have evolved and how they influence modern medical decision-making and ethical discussions. Results: A major turning point occurred in the 1980s when Jack Kevorkian’s assisted suicide device was made, raising concerns in courts, including the Supreme Court cases of Vacco v. Quill (1997) and Washington v. Glucksberg (1997), which ultimately ruled that the legality of physician-assisted suicide should be determined by individual states. Oregon’s 1999 “Death with Dignity” law set the standard and became evident in other states with similar legislation, showing a growing trend of acceptance of physician- assisted suicide in the US, while euthanasia remains legalized only in a few countries abroad. Conclusion: The current issue remains the debate between individual autonomy and fears of ethical misuse, along with possible consequences for palliative care. Providing thorough training to healthcare providers and ensuring that patients and families receive clear information about their choices must be a priority. A common approach to physician-assisted suicide may help standardize care and address ethical and practical challenges while emphasizing respect and compassion in end-of-life decisions.