Specific Lipidomic Shifts in Chronic Lymphocytic Leukemia at Diagnosis

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Authors

Julia Wojnicka · Medical University of Lublin

Michał Kiełbus · Medical University of Lublin

Paulina Mertowska · Medical University of Lublin

Sebastian Mertowski · Medical University of Lublin

Ewelina Grywalska · Medical University of Lublin

Piotr Sosnowski · Medical University of Lublin

Alicja Wielgosz

Abstract

Treatment-naïve CLL patients display distinct plasma lipidomic signatures indicative of disease-specific metabolic reprogramming. Integrated lipidomic and predictive pathway analyses suggest disruptions in lipid metabolic pathways and highlight carnitines and ether-linked phospholipids as biological markers warranting further investigation as potential CLL biomarkers.

Topics & Keywords

Metabolomics and Mass Spectrometry Studies Chronic Lymphocytic Leukemia Research Cancer, Lipids, and Metabolism

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Cancers

Volume 18, Issue 6, pp. 896-896

DOI: 10.3390/cancers18060896

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