P03.03 Dried antibody cocktails: setting the benchmark for fast and robust flow cytometric analysis in cell and gene therapy

samples from vaccinated patients, and that these predictions correlate well with ELISPOT data.We show how directed generation of epitope-TCR training data can improve predictive performance for specific antigens of interest.Across the different applications, we also demonstrate that identified tumor-specific T-cells can be tracked in vivo using TCR sequencing as a powerful means of immune monitoring after immunotherapy. ConclusionWe provide an overview of several concrete TCRbased immune monitoring applications in the field of immunotherapy in oncology.TCR repertoire analysis is a novel and accessible methodology for monitoring T-cell responses against a broad range of antigens from a single blood sample.This methodology can be used to filter and identify clinically-relevant TCRs for use in therapy development, immune biomarker analysis, or the development of companion diagnostics.MVH is an employee and SW, TB, PM are shareholders and directors of ImmuneWatch BV.