P08.11 Integrative molecular and spatial analysis of endothelial cell heterogeneity in clear cell renal cell carcinoma

ferent patterns were observed.Using a custom-panel built from DEG identified in the snRNA-seq dataset, vessels corresponding to the disctint EC clusters were identified.Conclusions The results of this work indicate a link between molecular endothelial cell heterogeneity and vascular patterns in ccRCC and suggest a functional heterogeneity linked to the vascular architecture.