Utility of blood biomarkers in inpatients with West Nile virus infection: an exploratory study

In this exploratory cohort of patients with neuroinvasive WNV infection, subtle alterations in erythrocyte indices and monocyte counts were associated with a septic clinical presentation, whereas inflammatory indices showed only non-significant trends. These findings suggest that routine hematological parameters may contribute to the early phenotypic characterization of WNV infection. Larger, multicenter studies are warranted to confirm these observations and to clarify the prognostic value of routine hematological and inflammation-related biomarkers in this setting.