Strengthening antimicrobial resistance policies: lessons from the design and implementation phase of the EU-JAMRAI 2 Sustainability Guidance Tool

Antimicrobial resistance (AMR) threatens global health and requires sustained, integrated responses beyond short-term initiatives. EU-JAMRAI 2 mobilises over 120 partners to produce scalable solutions aligned with One Health priorities. To ensure long-term uptake, the French Ministry of Health developed a Sustainability Guidance Tool (SGT) supporting work packages in defining priority outcomes, anticipating risks, and embedding results into national systems. This dynamic approach, based on iterative revision and alignment with National Action Plans (NAPs), strengthens governance, financing, monitoring, and policy integration. By summarising early lessons from design and implementation, this article informs future transnational AMR policy planning and sustainability strategies.