Dopaminergic manipulation modulates frequency-specific EEG connectivity patterns: evidence from a single dose drug challenge study

Our findings in the gamma band support the long-standing hypothesis that dopaminergic action on large-scale neural networks follows an inverted U-shaped curve. The linear pattern of our findings in the delta, alpha, and low-beta frequency bands reflect possible relevant effects for psychotic symptoms. However, our findings are difficult to relate to existing findings in patients. Our results highlight the need for further prospective studies in patients to better understand the relationship between dopaminergic effects and ICMs.