Dimensional Associations Between Conduct Problems and Brain Structure Across 18 International Cohorts in ENIGMA

CPs were associated with subtle, yet widespread, alterations in brain structure. Findings overlapped with differences observed in categorically-measured conduct disorder, but novel associations with cortical thickness were identified. This provides further evidence that neuroanatomical differences are not limited to youths with clinically-elevated CPs. Our findings have potential implications for neurocognitive models of CPs as they extend beyond the regions highlighted in these models.