Ifosfamide-Induced Encephalopathy in a Very Young Child With Rhabdomyosarcoma: Case Report and Literature Review

20260 citationsJournal Article

Authors

Roberta Koronica · Radiation Oncology Institute

Francesco De Leonardis · Radiation Oncology Institute

Mariachiara Servedio · Radiation Oncology Institute

Chiara Novielli · Radiation Oncology Institute

Enza Pentassuglia · Radiation Oncology Institute

Nicola Santoro · Radiation Oncology Institute

Abstract

IIE is a rare but severe side effect of ifosfamide infusion, and clinical manifestations in children may be misunderstood. We speculate that pharmacogenetic testing may be warranted in very young children to prevent severe IIE.

Topics & Keywords

Chemotherapy-induced organ toxicity mitigation Acute Lymphoblastic Leukemia research Carcinogens and Genotoxicity Assessment

Publication Details

Published in: Journal of Pediatric Hematology/Oncology

Volume 48, Issue 3, pp. 139-141

DOI: 10.1097/mph.0000000000003183

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Ifosfamide-Induced Encephalopathy in a Very Young Child With Rhabdomyosarcoma: Case Report and Literature Review

Authors

Abstract

Topics & Keywords

Publication Details