Effects of Exercise on Cognitive Impairment in Patients Receiving Chemotherapy: A Multicenter Phase III Randomized Controlled Trial

20260 citationsJournal Article

Authors

Karen M. Mustian · University of Rochester Medical Center

Po‐Ju Lin · University of Rochester Medical Center

Alisha Chakrabarti · University of Rochester Medical Center

Lindsey Jean Mattick · University of Rochester Medical Center

Stephen Rajan Samuel · Mount Vernon Nazarene University

Umang Gada · University of Rochester Medical Center

Brian J. Altman

Abstract

EXCAP may reduce CRCI and mental fatigue, particularly in patients receiving 2-week cycles of chemotherapy. A healthy inflammatory response, characterized by increases in both proinflammatory and anti-inflammatory cytokines, is associated with less cognitive impairment during chemotherapy.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of the National Comprehensive Cancer Network

Volume 24, Issue 3, pp. 91-99

DOI: 10.6004/jnccn.2025.7118

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