Healing Wounds

Wound healing has long provided a framework for studying cell and tissue dynamics, yet early contributions are often overlooked. Revisiting research from the late 19th to mid-20th centuries reveals enduring questions on migration versus proliferation, individual versus collective motion, and chemical versus mechanical drivers. Concepts such as contractility, collective motility, and contact inhibition illustrate the continuity of debate across generations. By reconnecting these foundational studies with modern advances, we highlight persistent gaps and offer historical context to guide future research.