Clinical features of androgen abuse withdrawal in men during the first year of cessation: a community dwelling study

Among men in the first year after stopping androgen abuse, psychological symptoms and reduced quality-of-life were most strongly associated with psychiatric comorbidity than biochemical recovery. These findings challenge the assumption that androgen withdrawal symptoms are predominantly driven by hypogonadism, and supports developing psychological and behavioural interventions, rather than pharmacological, to support androgen withdrawal in men.