Resolution of PR3-ANCA-associated vasculitis after antibiotic treatment of subacute bacterial endocarditis: a case report

Subacute endocarditis can be complicated by immune responses that mimic ANCA vasculitis. The European Society of Cardiology recommends evaluation by ECG and echocardiogram in vasculitides. The Vasculitis Foundation notes that in refractory vasculitides, clinicians should evaluate whether infection is mimicking vasculitis. However, there is no guideline for routine blood cultures in AAV. Ultimately, treatment with antibiotics alone led to seronegativity of ANCA and resolution of pathology to the affected extracardiac organs.