Patterns of HIV-1 Viral Load Suppression and Drug Resistance During the Dolutegravir Transition: A Population-based Longitudinal Study

20260 citationsJournal Articlehybrid Open Access

Authors

Marc Martín · Johns Hopkins University

Alexandra Blenkinsop · NIHR Imperial Biomedical Research Centre

Michelle Moffa · Johns Hopkins University

Steven James Reynolds · Johns Hopkins University

Fred Nalugoda · Rakai Health Sciences Program

Thomas C Quinn · Johns Hopkins University

Godfrey Kigozi

Abstract

Viral suppression increased during the DTG-transition with minimal emerging intermediate/high-level resistance. Falling resistance among treatment-experienced PLHIV underscores the role of ART adherence in reducing viremia. The emergence of inS153Y justifies continued surveillance.

Topics & Keywords

HIV/AIDS drug development and treatment HIV Research and Treatment HIV-related health complications and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Infectious Diseases

DOI: 10.1093/cid/ciag161

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