IL10RB expression in cancer cells is associated with evolutionary changes to solidify treatment resistance

20260 citationsJournal Articlediamond Open Access

Authors

Chie Kudo-Saito · National Cancer Centre Japan

Hiroki Ozawa

Hiroshi Imazeki

Hitomi Masuda · Japan Bio Products (Japan)

Aki Takaiwa · Japan Bio Products (Japan)

Masayoshi Toyoura · Japan Bio Products (Japan)

Abstract

This study revealed that IL10RB is a key molecule in cancer intractability after achieving snail-induced EMT. Targeting IL10RB may be a promising strategy for improving clinical outcomes in the treatment of cancer.

Topics & Keywords

Cancer Cells and Metastasis Wnt/β-catenin signaling in development and cancer Cancer Research and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BJC Reports

Volume 4, Issue 1

DOI: 10.1038/s44276-026-00211-3

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