Integrative transcriptomic profiling reveals molecular signatures of disease progression from gastroesophageal reflux disease to Barrett's esophagus: A foundation for single-cell resolution studies

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Authors

Shanshan Jiang · The Fifth People's Hospital of Anyang

Xiumin Wang · The Fifth People's Hospital of Anyang

Yujun Chen · The Fifth People's Hospital of Anyang

Weihua Dong · The Fifth People's Hospital of Anyang

Jing Xu · Kaifeng University

Chunlan Zhang · Guangxi Medical University

Chun Zhou

Abstract

This comprehensive transcriptomic study unveils the molecular complexity underlying GERD-to-Barrett's esophagus progression, identifying key genes and pathways that drive pathological transformation.

Topics & Keywords

Esophageal Cancer Research and Treatment Eosinophilic Esophagitis Single-cell and spatial transcriptomics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: SLAS TECHNOLOGY

Volume 38, pp. 100412-100412

DOI: 10.1016/j.slast.2026.100412

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