A Randomized Controlled Clinical Study on Efficacy of Amra Pallava in Navajata Kamala w.s.r. to Physiological Jaundice

Introduction: Neonatal Jaundice is the yellowish discoloration of skin and mucus membranes due to accumulation of bilirubin in the blood. Ayurveda explains Neonatal Jaundice as Koshtasrita Kamala and the treatment of choice is Virechana. As Navajata is an age where Virechana is contraindicated, certain Dravyas which have Pitta Shamana property are used. There are many formulations mentioned for Kamala in Children in Arogya Raksha Kalpa Druma, an exclusive Ayurvedic text of Kaumarabhritya. One such drug is Amra Pallava with Narikela Jala Materials and Methods: A total of 30 neonates were taken for the study and divided into two groups with 15 neonates each: Group A was treated with Amra Pallava 125mg TID along with quantity sufficient Narikela Jala for 5days and Group B was treated with Intermittent Phototherapy. To assess its effectiveness, assessment was done before treatment (0th day), after treatment (5th day) and after follow up (9th day) using Total Serum Bilirubin levels and Kramer’s index. Results: Statistical analysis was done after intervention. The assessment as done based on Total Serum Bilirubin levels and Kramer’s index for Neonatal Jaundice. It showed that both the groups were equally effective in Reducing Total Serum Bilirubin. Discussion: Amra Pallava has a Rasayana effect on Yakrit. Amra Pallava has Mangiferin, Citronellal which have Hepato-protective activity by their anti-oxidant properties.