Dysplasia in sessile serrated lesions: frequency, interobserver variability and added value of immunohistochemistry

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Authors

Valentina Angerilli · Radboud University Nijmegen

M. Elisa Vink‐Börger · Radboud University Nijmegen

Nanette S van Roermund · Amsterdam University Medical Centers

Gesina van Lijnschoten · Eurofins (Netherlands)

Chantal C.H.J. Kuijpers · Nationwide Mutual Insurance Company (United States)

Nicole C.T. van Grieken · Vrije Universiteit Amsterdam

Matteo Fassan

Abstract

The diagnosis of SSLd appears to have good reproducibility among pathologists and positive diagnostic trends that are observed in recent years. MLH1 is the only IHC marker with robust clinical utility to identify SSLd that do not meet the morphologic criteria for overt dysplasia but should be used only in selected cases due to its low prevalence.

Topics & Keywords

Cutaneous Melanoma Detection and Management Salivary Gland Tumors Diagnosis and Treatment Oral Health Pathology and Treatment

Publication Details

Published in: Histopathology

DOI: 10.1111/his.70135

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Dysplasia in sessile serrated lesions: frequency, interobserver variability and added value of immunohistochemistry

Authors

Abstract

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Publication Details