Clinical Course and Obstetric Outcomes of COVID-19 in Pregnant Women in the Hospitals of Osh Region: a Retrospective Analysis

COVID-19 infection caused by SARS-CoV-2 poses a particular risk to pregnant women and may complicate the course of pregnancy and delivery. To investigate the clinical features of COVID-19 and obstetric outcomes in pregnant women hospitalized in healthcare facilities of Osh region. A retrospective analysis of medical records of 113 pregnant women with laboratory-confirmed SARS-CoV-2 infection who were hospitalized in 2020 was conducted. Clinical course of COVID-19, obstetric complications, delivery methods, and pregnancy and delivery outcomes were evaluated. Descriptive statistics were used. In the majority of patients, the disease was mild to moderate; however, severe COVID-19 was associated with the development of obstetric complications. The most common pregnancy complications included false labor, threatened preterm delivery, anemia, and preeclampsia. Cesarean section was performed in 72 (63.2%) cases. Preterm delivery occurred in 53.1% of patients. Three maternal deaths (2.7%) were recorded in the study group, all associated with severe COVID-19 complicated by bilateral pneumonia and coagulopathy. Pregnant women with COVID-19 should be considered a high-risk group for developing obstetric complications, requiring early risk stratification and active inpatient monitoring.