Exploring Polyherbal Therapeutic Potential of Hingwashtak Churna in Managing Primary Dysmenorrhea by Network Pharmacology Approach

Primary dysmenorrhea (PD) is a prevalent menstrual disorder affecting a significant portion of the female population.It is primarily characterized by severe cramping and abdominal pain, driven by the excessive secretion of prostaglandins during menstruation.Hingwashtak Churna, an Ayurvedic polyherbal formulation, is widely used to manage digestive and menstrual disorders.This study explores the therapeutic potential of Hingwashtak Churna in managing PD through network pharmacology approach.By analyzing the bioactive compounds and their molecular targets, the research provides insight into the interactions between the herbs and the underlying dysmenorrhea-associated pathways.Results indicated that Hingwashtak Churna has a multi-target action, influencing various genes and pathways related to prostaglandin synthesis, inflammation, and immune response, offering potential relief from PD symptoms.