Impact of Postnatal Changes in Creatinine Levels on Plasma Gentamicin Concentrations in Neonates

20260 citationsJournal Articlehybrid Open Access

Authors

Haruka Tsushita · Oita University Hospital

Ryota Tanaka · Oita University Hospital

Masanori Inoue · Oita University

Ryosuke Tatsuta · Oita University Hospital

Shintaro Kishimoto · Oita University

Tomoki Maeda · Oita University

Naoki Yoshikawa ·

Abstract

PMA-based dosing appears to be preferable for determining initial GM dosing on postnatal day 0, whereas Cr-based renal function parameters may be more effective for guiding maintenance dosing.

Topics & Keywords

Antibiotics Pharmacokinetics and Efficacy Neonatal and Maternal Infections Infant Nutrition and Health

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Pharmaceutical Research

DOI: 10.1007/s11095-026-04045-z

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