Genomic Landscape of Myoepithelial Carcinoma Tumors

20260 citationsJournal Article

Authors

Mayukha Kashyap · Children's Cancer Therapy Development Institute

Hollis Wright · Children's Cancer Therapy Development Institute

JiHyeon Byun · Children's Cancer Therapy Development Institute

Geoffrey B. Alintoff · Children's Cancer Therapy Development Institute

Anandhi Mandi · Children's Cancer Therapy Development Institute

Melvin Lathara · ZRT Laboratory

Ganapati Srinivasa

Abstract

Despite sharing a chromosomal translocation partner (the EWSR1 gene) with sarcomas, MECA are most related to other salivary carcinomas. Further exploration of IGF1R as a therapeutic target in MECA is warranted. We also make available the 27 patients' next generation DNA exome and RNA sequencing through the EGA Repository.

Topics & Keywords

Salivary Gland Tumors Diagnosis and Treatment Salivary Gland Disorders and Functions Soft tissue tumor case studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Oral Diseases

DOI: 10.1111/odi.70293

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