Neuropsychiatric Symptom Clusters and Their Association With Brain Structure in Alzheimer Disease

20260 citationsJournal Article

Authors

Daniel Kapustin · Centre for Addiction and Mental Health

Neda Rashidi-Ranjbar · St. Michael's Hospital

Wang, Wei Neng; Chang, Juin Jen; Shieh, Jhy Yuan; Chen, Jhy Hwa · Centre for Addiction and Mental Health

Malcolm A. Binns · University of Toronto

Paula McLaughlin · Nova Scotia Health Authority

Agessandro Abrahão · Sunnybrook Health Science Centre

David Grimes

Abstract

<b>Conclusion:</b> NPS in AD separate into hyperactivity, psychosis, neurovegetative, and affective clusters, supporting a cluster-based paradigm linking co-occurring behavioral symptoms with brain structure and functional decline.

Topics & Keywords

Dementia and Cognitive Impairment Research Mental Health Research Topics Functional Brain Connectivity Studies

Publication Details

Published in: The Journal of Clinical Psychiatry

Volume 87, Issue 2

DOI: 10.4088/jcp.25m16192

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Neuropsychiatric Symptom Clusters and Their Association With Brain Structure in Alzheimer Disease

Authors

Abstract

Topics & Keywords

Publication Details