CHEK2 germline variants in B-cell precursor acute lymphoblastic leukemia: findings in Mexican pediatric patients

Our findings and those described in the literature suggest that <i>CHEK2</i> may play a role in the germline origin of childhood pre-B ALL in specific populations. However, this study provides preliminary evidence of pre-B ALL predisposition in Mexican children with <i>CHEK2</i> GVs that needs replication in a larger cohort to obtain accurate estimations.