Additional file 3: Figure S3. of Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells

Microarray validation. a The distribution of the frequency of the fold change of the expression of genes from WT versus HP1β KO ESCs. The curve represents the cumulative percentage, which enables determination of the fold changes which are statistically significant. P values corresponding to 0.05 and 0.005 are shown (light squares). b Expression levels, measured by RT-qPCR, of nine representative genes shown next to the corresponding microarray results for HP1α KO (white) and HP1β KO (left) ESCs. The linear regression and correlation were calculated between the two data sets (r = 0.8). c Same as in (b) with the EB samples derived from WT, HP1α KO, and HP1β KO EBs. (PDF 152 kb)