Comparative Effectiveness of Antihypertensive Medications in Children With Chronic Kidney Disease

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Authors

Michelle Denburg · Children's Hospital of Philadelphia

Amy Goodwin Davies · Children's Hospital of Philadelphia

Mitchell Maltenfort · Children's Hospital of Philadelphia

Mark Mitsnefes · Cincinnati Children's Hospital Medical Center

Joseph T. Flynn · Seattle Children's Hospital

Alicia M. Neu · Johns Hopkins University

B. Dixon

Abstract

In this comparative-effectiveness study, RAASi was associated with lower risk of CKD progression and better blood pressure control compared to CCB. Findings support first-line use of RAASi for antihypertensive treatment in pediatric CKD.

Topics & Keywords

Chronic Kidney Disease and Diabetes Acute Kidney Injury Research Blood Pressure and Hypertension Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Pediatrics

DOI: 10.1001/jamapediatrics.2026.0207

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