Short Antibiotic Treatment for Coagulase-negative Staphylococcal Sepsis in Premature Infants: A Multicenter Noninferiority Study

20260 citationsJournal Article

Authors

Esther J. d’Haens · Isala

S. B. Debast · Isala

John W.A. Rossen · University Medical Center Groningen

Douwe H. Visser · Emma Kinderziekenhuis

Klasien A. Bergman · University Medical Center Groningen

Jacqueline U.M. Termote · Wilhelmina Children's Hospital

Tom F.W. Wolfs ·

Abstract

The relapse rate in uncomplicated CoNS sepsis was extremely low (<1%), even with short-course treatment. In premature infants with uncomplicated CoNS sepsis, shorter antibiotic treatment is noninferior to longer treatment, confirming its safety and effectiveness.

Topics & Keywords

Neonatal and Maternal Infections Sepsis Diagnosis and Treatment Preterm Birth and Chorioamnionitis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Pediatric Infectious Disease Journal

DOI: 10.1097/inf.0000000000005209

Field-Weighted Citation Impact: 0.00