Aperiodic and periodic neural activity during sleep in autism spectrum disorders

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Authors

Noemi Mazzoni · Università degli Studi eCampus

Eva-Maria Kurz · Uppsala University

Nicola Cellini · University of Padua

Luciana Ciringione · University of Trento

Margherita Calderan · University of Padua

Giuseppe Gallitto · Essen University Hospital

Simona de Falco ·

Abstract

Our study provides novel electrophysiological evidence for a nuanced, sleep-related dysregulation in ASD that varies by sleep stage and cortical region, and subtly diverges from patterns observed in NT controls. Given the mechanistic relevance of sleep for neurodevelopment and circuit homeostasis, these findings offer valuable insights into sleep-related neurophysiological dysregulation in ASD.

Topics & Keywords

Sleep and Wakefulness Research Autism Spectrum Disorder Research Genetics and Neurodevelopmental Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Medicine

DOI: 10.1186/s12916-026-04771-6

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