Healthcare Workers’ Perspectives on Factors Influencing Compliance with Infection Prevention and Control Practices at Katavi Regional Referral Hospital, Tanzania

Infection prevention and control remains an essential component of effective healthcare delivery and disease prevention. This study aimed to explore healthcare workers’ perspectives on factors influencing compliance with infection prevention and control practices in Katavi Regional Referral Hospital, Tanzania. With a qualitative approach, we aimed to enable a broader narrative, gain a more detailed understanding of IPC practices, and identify experiences that may be overlooked in a forced-choice questionnaire. A cross-sectional design using a phenomenological approach was employed. An interview guide was used to collect data from 19 participants (five doctors, four nurses, four laboratory practitioners, and six from administration positions; ward in-charges, quality improvement officers and administrative officers) between 24 July 2025, and 23 August 2025. Among participants, nine were the key informants, and 10 were involved in in-depth interviews. Thematic analysis revealed that the availability of IPC supplies, desire for personal and patient protection, high patient volume, awareness of IPC protocols, institutional support, supportive supervision, and HCWs’ attitudes towards IPC activities were factors influencing IPC compliance. Strengthening structured supervision, ensuring a constant supply of IPC materials, and investing in continuous IPC capacity building may be an important approach in enhancing compliance with IPC practices and reducing hospital-associated infection risk in Katavi Regional Referral Hospital and similar resource-limited healthcare settings.