Stable isotope labeling reveals that sugars are direct precursors to several toxicants and flavorings in cigarette smoke

Based on our findings on sugars as precursors of harmful and flavored compounds, we propose to ban the addition of sugars to cigarettes, and other combustible tobacco products. Imposing maximum allowable levels on sugars that are naturally present in tobacco could also be considered, as they also lead to harmful compounds and impart a flavor.This study adds to the body of evidence that sugars present in cigarette tobacco are precursors of harmful and flavored constituents of cigarette smoke. Regulation of sugars, such as banning added sugars and setting limits on natural sugars, may serve to protect public health.