Single-cell inflammatory signaling defines a novel CEP135+ endothelial subtype associated with glioma progression

20260 citationsJournal Articlegold Open Access

Authors

Ziteng Ji · Xuzhou Medical College

Ulf D. Kahlert · University Hospital Magdeburg

Sijie Wu · 181st Hospital of Chinese People's Liberation Army

Claudia A. Dumitru · Otto-von-Guericke-Universität Magdeburg

Erol Sandalcioglu · Otto-von-Guericke-Universität Magdeburg

Jidong Zhang · Xuzhou Medical College

Dacheng Wang

Abstract

This study identified a innovative CEP135+inflammation-associated endothelial cell subtype and established CEP135 as a key biomarker linking endothelial inflammation reprogramming, tumor progression, and adverse clinical outcomes.

Topics & Keywords

Single-cell and spatial transcriptomics Glioma Diagnosis and Treatment Neuroinflammation and Neurodegeneration Mechanisms

Publication Details

Published in: Translational Oncology

Volume 67, pp. 102742-102742

DOI: 10.1016/j.tranon.2026.102742

Field-Weighted Citation Impact: 0.00

Command Palette

Single-cell inflammatory signaling defines a novel CEP135+ endothelial subtype associated with glioma progression

Authors

Abstract

Topics & Keywords

Publication Details