Multicenter Assessment of Postoperative Mastocheck® Dynamics Following Curative Breast Cancer Surgery

Across two independent cohorts with complementary postoperative assessment strategies, Mastocheck^® values consistently decreased after breast cancer surgery and shifted to, or were maintained below, the predefined diagnostic cut-off. These findings reproduce and extend prior single-institution observations, supporting the reproducibility of Mastocheck^® postoperative decline dynamics and cut-off transitions across independent cohorts. This study did not evaluate recurrence detection, imaging concordance, or survival outcomes, and therefore does not establish clinical surveillance performance.