Tech-Based interactive E-module: a flexible learning material in biochemistry

This study reports the design, development, and evaluation of a Tech-Based Interactive E-Module (TBIEM) for teaching Biochemistry, with a focus on Lipids. Following the ADDIE model and using the Research and Development framework of Borg and Gall, we created a flexible learning tool on the Adapt platform and evaluated it with second-year Bachelor of Secondary Education (BSEd) science majors from three campuses of Batangas State University The National Engineering University (Lipa Campus, Nasugbu Campus, and Malvar Campus) in the Philippines ( N = 107). A one-group pretest-posttest design measured learning gains; a validated questionnaire assessed the module's quality across content, media integration, interactivity, adaptability, and accessibility; and focus groups captured students' perceptions. Implementation of the TBIEM was associated with large and statistically significant gains in Biochemistry scores (mean improvement ≈ 15 points out of 30, Cohen's d ≈ 3.0, normalized gain ⟨g⟩ ≈ 0.72). Students rated the module very highly across all five dimensions, and a moderate positive correlation emerged between feature ratings and learning gains. These findings suggest that the TBIEM is an effective, engaging, and flexible tool for biochemistry education, with the potential to support learners from diverse backgrounds and with varying prior knowledge.