Bacillus spore probiotics for alleviating functional constipation in children: a randomized, double-blind, placebo-controlled trial

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Authors

Hanh Thi Luong Nguyen · National Institute of Nutrition

Hang Thi Hoang · National Institute of Nutrition

Dung Phuong Le · Hanoi University of Pharmacy

Truong Quoc Duong · Thai Nguyen University

Ngoc Thi Ho Vuong · National Institute of Nutrition

Mai Tuyet Truong · National Institute of Nutrition

Hung Trong Nguyen

Abstract

Multi-strain Bacillus spore probiotics alleviate functional constipation, improve immune markers, and modulate gut microbiota in children, supporting their potential as effective microbiome-targeted interventions.

Topics & Keywords

Gastrointestinal motility and disorders Probiotics and Fermented Foods Infant Health and Development

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Communications Medicine

Volume 6, Issue 1

DOI: 10.1038/s43856-026-01517-6

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