Correcting Misaligned Risk Comparisons Between LDL-C Levels and Polygenic Risk Scores

FIGURE 1 Coronary Artery Disease HRs Across Polygenic Risk Score and LDL Cholesterol LevelsHRs for coronary artery disease by polygenic risk score group and LDL cholesterol level using a genome-wide polygenic risk score (Allelica), with low polygenic risk score and LDL cholesterol <100 mg/dL as the reference group.CAD = coronary artery disease; LDL-C