Ki-67 staining pattern as a prognostic biomarker for advanced acral melanoma

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Authors

Marcel Arakaki Asato · Universidade Federal de Mato Grosso do Sul

Isabeli Joaquim Contel · Universidade Estadual Paulista (Unesp)

Francisco Alves Moraes Neto · Hospital Amaral Carvalho

Juliana Polizel Ocanha-Xavier · Universidade Estadual Paulista (Unesp)

Nathália Silva Carlos Oliveira · Universidade Federal Fluminense

Maxwell A. Fung · University of California, Davis

Mariangela Esther Alencar Marques

Abstract

The present analysis highlights the importance of Ki-67 staining patterns as a potential prognostic marker among ACM. High Ki-67 positive nuclei were associated with worse outcomes (death), particularly in staining patterns before and after mitosis (NP1, NP4, and NP5).

Topics & Keywords

Cutaneous Melanoma Detection and Management Nonmelanoma Skin Cancer Studies Cancer and Skin Lesions

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Anais Brasileiros de Dermatologia

Volume 101, Issue 2, pp. 501298-501298

DOI: 10.1016/j.abd.2026.501298

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