Interpreting nonsignificant findings: Reassessing the safety of self-locking standalone cages in octogenarian patients undergoing ACDF

concluded that anterior cervical discectomy and fusion (ACDF) using a self-locking standalone cage (ROI-C) is a "safe and viable" option for patients aged 80 years, on the basis of the absence of statistically significant differences in complications, fusion, or recovery between age groups [1].However, both the statistical reasoning and the broader evidence base indicate that this conclusion should be interpreted with caution.