Progranulin Regulates Protein Synthesis in Myocytes Through an Ephrin Type A Receptor 2‐Dependent Pathway

20260 citationsJournal Article

Authors

Kkl Chan · National Cheng Kung University Hospital

Hiong‐Ping Hii · Min-Hwei College of Health Care Management

Hsin‐Yu Kuo · National Cheng Kung University Hospital

Chung‐Teng Wang · National Cheng Kung University

Kai‐Pi Cheng · National Cheng Kung University Hospital

Horng‐Yih Ou · National Cheng Kung University Hospital

Hung‐Tsung Wu

Abstract

Progranulin acts as a novel regulator of skeletal muscle metabolism, which enhances protein synthesis through EphA2-mediated activation of the mTOR signaling cascade.

Topics & Keywords

Amyotrophic Lateral Sclerosis Research Hereditary Neurological Disorders Sphingolipid Metabolism and Signaling

Publication Details

Published in: Acta Physiologica

Volume 242, Issue 4, pp. e70182-e70182

DOI: 10.1111/apha.70182

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Progranulin Regulates Protein Synthesis in Myocytes Through an Ephrin Type A Receptor 2‐Dependent Pathway

Authors

Abstract

Topics & Keywords

Publication Details