Therapeutic Clozapine Monitoring Using Dose-Related Reference Range

20260 citationsJournal Article

Authors

K. Ferchichi · Tunis University

S. Ben-Hammamia · Tunis University

Mouna Ben Sassi · Tunis University

Mouna Daldoul · Tunis University

Hanène El Jebari · Tunis University

Mohamed Zouari · Tunis University

Rim Charfi · Tunis University

Abstract

These plasma clozapine levels aligned more with the DRR than with the TRR, particularly when individual dosing was considered. The DRR may offer higher precision in guiding therapeutic decisions and dose adjustments. Further prospective studies are warranted to optimize the use of the DRR in clinical practice and validate the value of the DRR in predicting clozapine efficacy and safety.

Topics & Keywords

Schizophrenia research and treatment Treatment of Major Depression Neurotransmitter Receptor Influence on Behavior

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Therapeutic Drug Monitoring

DOI: 10.1097/ftd.0000000000001451

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