Total Sealing Technique Using an Advanced Bipolar Vessel-Sealing System in Axillary Lymph Node Dissection: A Technical Note and Review of Clinical and Economic Outcomes

<b>Background</b>: Axillary lymph node dissection (ALND) remains necessary for selected patients with breast cancer but is associated with lymphatic morbidity, including seroma formation and breast cancer-related lymphedema (BCRL). The Total Sealing Technique (TST) is a technique-centered operative concept that emphasizes systematic sealing of lymphatic and vascular structures during ALND. <b>Methods</b>: This review integrates mechanistic rationale and clinical evidence derived from comparative cohort studies evaluating TST (using advanced bipolar vessel-sealing systems) versus conventional electrocautery (CONV). Key perioperative and long-term outcomes are summarized quantitatively. <b>Results</b>: In a comparative cohort of total mastectomy with ALND, TST significantly reduced total drainage volume (360.5 ± 187.9 vs. 820.6 ± 661.6 mL; <i>p</i> < 0.001) and shortened time to drain removal (4.8 ± 1.3 vs. 6.8 ± 2.1 days; <i>p</i> < 0.001). Postoperative hospital stay was reduced by 3.7 days on average (5.9 ± 1.3 vs. 9.6 ± 3.4 days; <i>p</i> < 0.001). The incidence of seroma decreased from 65.9% to 28.6% (<i>p</i> = 0.001), with fewer aspiration procedures (1.8 vs. 4.6 per patient; <i>p</i> = 0.022). Importantly, long-term follow-up demonstrated a statistically significant reduction in BCRL incidence (2.9% vs. 22.2%; <i>p</i> = 0.028). Operative time and blood loss were not increased. <b>Conclusions</b>: Current single-center data indicate that TST is associated with substantial reductions in postoperative lymphatic morbidity and a statistically significant decrease in BCRL incidence. While independent multicenter validation is warranted, TST represents a reproducible technique-centered approach with meaningful clinical impact in ALND.