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Sex-Specific Metabolic Remodelling in Infantile Haemangioma
2026
0 citations
Journal Article
diamond Open Access
Field-Weighted Citation Impact:
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Sex-Specific Metabolic Remodelling in Infantile Haemangioma | Researchclopedia
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MP Technologies (United States)
Bioinformatics revealed differential expression in LXR/RXR activation
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MP Technologies (United States)
DHCR24 signalling
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MP Technologies (United States)
and mitochondrial dysfunction. Oxidative phosphorylation complexes I and IV were highly expressed in female proliferating IH
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MP Technologies (United States)
with increased oxidative stress. Further
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MP Technologies (United States)
we validated the regulation of cholesterol homeostasis in IH using PCR array. Proliferation
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MP Technologies (United States)
migration and angiogenesis were upregulated in female lesions compared to males
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MP Technologies (United States)
possibly explaining the higher severity and incidence in females.
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MP Technologies (United States)
In summary
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MP Technologies (United States)
we have generated the proteomic landscape of IH in both sexes identifying altered pathways and potential therapeutic targets.
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MP Technologies (United States)