Mechanisms underlying the protective effects of San‐Bai decoction against <scp>UV</scp> radiation on the skin

USBT2627 suppresses melanin accumulation in vitro and protects skin against UV exposure in both in vitro and in vivo models; multiple components, targets and pathways of SBD act together to confer its protective effect against UV exposure. These findings highlight a significant potential of topical USBT2627 in protecting skin against UV exposure. Additionally, this study showcases the value of a systems network approach in elucidating the mechanisms of this herbal blend, offering valuable references for further research aimed at developing TCM-based products.