The Paediatric Intensive Care Adaptive Platform Trial (PIVOTAL): Turning Pediatric Critical Care Practice Into Clinical Research

20260 citationsJournal Articlehybrid Open Access

Authors

M. J. Peters · Great Ormond Street Hospital

Paul Mouncey · Intensive Care National Audit & Research Centre

Alexina J. Mason · Intensive Care National Audit & Research Centre

Tasnin Shahid · Intensive Care National Audit & Research Centre

Padmanabhan Ramnarayan · Great Ormond Street Hospital for Children NHS Foundation Trust

Samiran Ray · Great Ormond Street Hospital

Katherine Brown

Abstract

PIVOTAL aims to bridge the gap between clinical care and research, providing a sustainable infrastructure to deliver timely, inclusive, and practice-changing evidence in pediatric critical care. Recruitment started in March 2026.

Topics & Keywords

Sepsis Diagnosis and Treatment Childhood Cancer Survivors' Quality of Life Ethics and Legal Issues in Pediatric Healthcare

UN Sustainable Development Goals

Industry, innovation and infrastructure

Publication Details

Published in: Pediatric Critical Care Medicine

DOI: 10.1097/pcc.0000000000003937

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