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Galen of Pergamon (129–216 CE) was one of the most influential physicians of antiquity, whose anatomical and physiological concepts shaped medical thought for many centuries. His descriptions of the eye and the mechanism of vision represent one of the earliest systematic attempts to explain the structure and function of the visual organ. Although Galen relied primarily on animal dissections and philosophical reasoning, his observations formed an important foundation for later developments in ophthalmology and the history of neuroscience. This study outlines Galen’s investigations into the anatomy of the eye and the mechanism of vision based primarily on the 1822 edition of De usu partium corporis humani . Galen produced one of the most detailed descriptions of the eye in antiquity, integrating anatomical observations with philosophical and geometrical concepts of vision. He regarded the crystalline lens as the principal organ of visual perception and interpreted the surrounding ocular structures as protective and supportive elements. His theory of vision, based on the transmission of pneuma from the brain to the eye, reflected broader ancient ideas about the relationship between physiology and vital forces. Although later scientific developments revised many of these concepts, Galen’s views profoundly influenced medical and anatomical thought for many centuries. • Galen produced one of the earliest detailed descriptions of ocular anatomy in antiquity. • He considered the crystalline lens the primary organ responsible for visual perception. • Vision was explained through the transmission of pneuma from the brain to the eye. • Galen’s concepts influenced anatomical and medical thought for more than a millennium.
Published in: Translational Research in Anatomy
Volume 43, pp. 100477-100477