PCSK9 and breast cancer survival: a Mendelian Randomization study

20260 citationsJournal Articlehybrid Open Access

Authors

Ville Salo · Oulu University of Applied Sciences

Johannes Kettunen · Oulu University of Applied Sciences

Stephen Burgess · University of Cambridge

Abstract

Potential reasons for the discrepant results are different genetic models, sample selection criteria, and the time-variability of HR estimates. They should be explored before considering PCSK9 a therapeutic target in BC patients.

Topics & Keywords

BRCA gene mutations in cancer Genetic Associations and Epidemiology Lipoproteins and Cardiovascular Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer Epidemiology Biomarkers & Prevention

DOI: 10.1158/1055-9965.epi-25-1569

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