Retraction Note: Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome

The Editor has retracted this article after concerns were raised regarding the statistical methodology used in the analysis of several key figures (Figs. 1-6, 2s, 4s, and 5s).Specifically, multiple aspects of the statistical analysis were found to be inappropriate or incorrectly applied -these include the use of t-tests instead of ANOVA, the lack of correction for multiple comparisons, sample size too small for valid statistical testing, technical replicates incorrectly averaged or treated as independent biological replicates, and missing or incomplete raw data for several panels.