Disordered Bile Acid Metabolism in Alcohol‐Related Hepatitis

20260 citationsJournal Articlehybrid Open Access

Authors

Luke D. Tyson · Imperial College Healthcare NHS Trust

Stephen Atkinson · Imperial College Healthcare NHS Trust

B Mullish · Imperial College Healthcare NHS Trust

Alexandros Pechlivanis · Imperial College London

Michael Allison · Addenbrooke's Hospital

Andrew Austin · Royal Derby Hospital

Katie Chappell

Abstract

Serum conjugated primary BAs accumulate in AH. Elevated HGF may detrimentally affect the hepatoprotective adaptive reduction in NTCP/increase in BSEP seen in cholestasis, contributing to the AH BA profile.

Topics & Keywords

Alcohol Consumption and Health Effects Liver Disease Diagnosis and Treatment Liver physiology and pathology

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: Alimentary Pharmacology & Therapeutics

DOI: 10.1111/apt.70616

Field-Weighted Citation Impact: 0.00

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